Vertex Pharmaceuticals: R&D Portfolio Management

Vertex Pharmaceuticals: R&D Portfolio Management Order Description Case specific questions: 1.Which of the project portfolio options currently facing Vertex do you favor? Why? Specifically, what two projects would you pursue? What should they do with the other two? (25%) 2.What criteria would you use to make the decision? What other information do you think that Bogner needs to make his decision? (25%) 3.How do you determine the financial implications of this decision? (25%) 4.Should any of these products be licensed? When and why should a drug be licensed? (25%) For the excluswe use of Y. ZHANGZO15. maximum HARVARDIBUSINESSiSCHOOL 9-703-489 REV: APRIL 2, 2004 STEPHEN P, BRADLEY JAMES WEBER The Pharmaceutlcal Industry: Challenges 1n the New Century