The operation of negative and positive feedback mechanisms in maintaining homeostasis
Compare and contrast the operation of negative and positive feedback mechanisms in maintaining homeostasis. Provide two examples of variables controlled by negative feedback mechanisms and one example of a process regulated by a positive feedback mechanism.
Sample Answer
Negative Feedback Mechanisms
- How they work: These mechanisms counteract a change. If a regulated variable increases, the body initiates responses to decrease it; conversely, if it decreases, the body initiates responses to increase it. This brings the variable back towards a set point or normal range.
- Examples:
- Blood Glucose Regulation: When blood sugar levels rise (e.g., after a meal), the pancreas releases insulin. Insulin stimulates the uptake of glucose by cells and its storage as glycogen in the liver, lowering blood sugar levels. Conversely, when blood sugar levels fall (e.g., during fasting), the pancreas releases glucagon, which stimulates the breakdown of glycogen in the liver, releasing glucose into the bloodstream and raising blood sugar levels.