Pediatric Asthma Survey

  1. Pediatric asthma survey, n = 50. Suppose that asthma affects 1 in 20 children in a population. You take an SRS of 50 children from this population. Can the normal approximation to the binomial be applied under these conditions? If not, what probability model can be used to describe the sampling variability of the number of asthmatics?
  2. Misconceived hypotheses. What is wrong with each of the following hypothesis statements?
    a) H0: μ = 100 vs. Ha: μ ≠ 110
    b) H0: x̄ = 100 vs. Ha: x̄ < 100 or could write as H0: x̄ >= 100 vs. Ha: x̄ < 100
    c) H0: p^ = 0.50 vs. Ha: p^ ≠ 0.50
  3. Patient satisfaction. Scores derived from a patient satisfaction survey are Normally distributed with μ = 50 and σ = 7.5, with high scores indicating high satisfaction. An SRS of n = 36 is taken from this population.
    a) What is the standard error (SE) of x for these data?
    b) We seek to discover if a particular group of patients comes from this population in which μ = 50. Sketch the curve that describes the sampling distribution of the sample mean under the null hypothesis. Mark the horizontal axis with values that are ±1, ±2, and ±3 standard errors above and below the mean.
    c) Suppose in a sample of n = 36 from this particular group of patients the mean value of x is 48.8. Mark this finding on the horizontal axis of your sketch. Then compute a z statistic for this scenario and make sure it matches your sketch.
    d) What is the two-sided alternative hypothesis for this scenario?
    e) Find the corresponding p-value for your z-statistic using Table B.
    f) Draw a conclusion for this study scenario based on your results.
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Sample Answer

 

1. Pediatric Asthma Survey

Given that asthma affects 1 in 20 children in the population, the probability of a child having asthma is ( p = \frac{1}{20} = 0.05 ). For a sample size of 50 children, the mean and variance of the binomial distribution can be calculated as ( \mu = np = 50 \times 0.05 = 2.5 ) and ( \sigma^2 = np(1-p) = 50 \times 0.05 \times 0.95 = 2.375 ). The standard deviation is ( \sigma = \sqrt{2.375} \approx 1.54 ).

Since the number of asthmatic children in the sample (2.5) is less than 10, the normal approximation to the binomial cannot be applied due to the sample being small and the success rate being low. Instead, the sampling variability of the number of asthmatics can be described using a Poisson distribution since the conditions for using the Poisson model (rare events and independent trials) are met.

2. Misconceived Hypotheses

a) The alternative hypothesis should be specific, stating whether the population mean is greater or less than the hypothesized value. It should be ( H_a: \mu \neq 100 ) or ( H_a: \mu &gt; 100 ) depending on the research question.

b) The null hypothesis should be based on population parameters, not sample statistics. It should be formulated as ( H_0: \mu = 100 ) against an alternative hypothesis that specifies a direction, such as ( H_a: \mu &lt; 100 ).

c) The null hypothesis should be based on a specific value and not estimated from the data. It should be ( H_0: p = 0.50 ) against an alternative hypothesis that specifies a deviation from this value, such as ( H_a: p \neq 0.50 ).

3. Patient Satisfaction

a) The standard error (SE) of the sample mean can be calculated as ( SE = \frac{\sigma}{\sqrt{n}} = \frac{7.5}{\sqrt{36}} = 1.25 ).

b) Under the null hypothesis where μ = 50, the sampling distribution of the sample mean follows a normal distribution with mean μ = 50 and standard error SE = 1.25. The curve would be bell-shaped with values marked at ±1.25, ±2.5, and ±3.75 around the mean.

c) Marking x̄ = 48.8 on the horizontal axis, the z-statistic can be calculated as ( z = \frac{48.8 – 50}{1.25} = -1.44 ). This value should align with the sketch.

d) The two-sided alternative hypothesis for this scenario would be ( H_a: μ \neq 50 ).

e) Finding the corresponding p-value for a z-statistic of -1.44 from Table B will provide information on the significance level of the sample mean being 48.8.

f) Based on the p-value obtained, a conclusion can be drawn regarding whether the particular group of patients significantly differs from the general population in terms of satisfaction scores at a confidence level chosen by comparing the p-value to the significance level α.

 

 

 

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