Immunohistochemical evaluation of (TROP-2) and (BRAF V600E) in papillary thyroid carcinoma, Hashimoto thyroiditis, Graves disease, (a clinicopathological study) in samples of Iraqi patients.
Aims of the study :
- To evaluate the expression of TROP-2 and BRAF V600E in Hashimoto’s and Graves’ diseases by immunohistochemistry and it’s relation to other parameters ( age , sex ) .
- To evaluate the expression of TROP-2 and BRAF V600E in papillary thyroid carcinoma and to determine the relationship between TROP-2 overexpression and the expression of the mutant BRAF V600E oncoprotein in papillary thyroid carcinoma.
- To correlate the expression of TROP-2 and BRAF V600E in papillary thyroid carcinoma with clinicopathological parameters ( age , sex , tumor size , presence of tumor capsule , presence of lymph node