Read the paper Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk.pdf and answer the following questions in your own words.
- Describe the symptoms of individuals with the common cold (Rhinovirus). What causes these symptoms?
- How do glucocorticoids affect the immune system?
- What is glucocorticoid resistance (GCR)? Propose a hypothesis for how cells acquire GCR.
- What are the two hypotheses tested in this paper?
- What was the relationship between stress and GCR?
- What do proinflammatory cytokines do? What relationship do they exhibit with GCR levels?
- What are examples of other inflammatory diseases? What implications do the results of this study have for them?