Biomarker Alzheimer's disease: Alternatively consider multiple, neurodegenerative diseases

Biomarker Alzheimer's disease: Alternatively consider multiple, neurodegenerative diseases • Name of biomarker: Brain volume /ml • Disease: Alzheimer's disease: alternatively consider multiple, neurodegenerative diseases. • Modality: In MRI • Comment: could consider brain Subregions e.g. hippocampus Report (including tables but excluding references and figures; figures to occupy no more than one page) • What does the selected imaging biomarker purport to measure? (accurate reporting) • How is it measured? (accurate reporting) • How is it best classified? (accurate reporting) • What are the key publications (reviews, meta- analyses, consensus guidelines etc) that describe the measurement and interpretation of this biomarker... • ...and what do they conclude? (accurate reporting) • Clarity of writing and organization of material • Professional standard of layout, formatting and citation